NR 565 Week 4 Midterm Exam Points

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Institution	NR 565 Advanced Pharmacology Fundamentals
Contributor	Nicole Albriton

Description

Week 1:

· Up to 21% of Asians are ultra-rapid 2D6 metabolizers, leading to:

· The National Standards of Culturally & Linguistically Appropriate Services are required to be implemented in all:

· Warfarin (coumadin) resistance may be seen in patients with VCORC1 mutation, leading to:

Week 2:

§ What is phase 3 trials: who do they run it on (Human safety & efficacy studies).

§ Off label drugs who are they approved by FDA. Off-label prescribing is:

§The U.S. Food & Drug Administration regulates:

§The ailment that generates the greatest over-the-counter annual drug sales is:

Week 3:

§ There is a narrow margin between first appearance of adverse reaction to AChE inhibitors & serious toxic effects. Adverse reactions that require immediate action include:

§ Beta blockers are prescribed for diabetics with caution because of their ability to produce hypoglycemia & block the common symptoms of it. Which of the following symptoms of hypoglycemia is not blocked by these drugs & so can be used to warn diabetics of possible decreased blood glucose?

· 60 year old male with TN beta-adrenergic antagonist, effect of the beta blocker do: reduce cardiac contractility, reduce HR and BP??

· HTN and BPH. Doxazosin. What are the drugs of choice for treating hypertension in older men with concomitant BPH?

Orthostatic hypotension is one of the main concerns when initiating alpha-1 blocker

· Define bioavailability?

Dose response curve answer choice

· A patient with anxiety & depression may respond to: Buspirone (Buspar) & an SSRI combined

· Dosage of Cymbalta and how do you adjust it:

· What route is effected with firs-pass Metabolized first pass in the liver:

· When two or more medications are prescribed that are highly protein bound, what is the clinical outcome? Coumadin and protein binding. What happens when you give two drugs together

· Coumadin and NSAID interact.

· Allergic Reaction that involved angioedema and what do you give. Epi?

o A potentially life-threatening adverse response to angiotensin-converting enzyme inhibitors is angioedema. Which of the following statements is true about this adverse response?

• to ace inhibitors. Patients who have angina, regardless of class, who are also diabetic, should be on:

· Class of drugs certain meds were

· What is a major barrier in fully understanding the racial differences in drug pharmacokinetics seen in American Indian or Alaskan Natives? more research is

needed to identify further racial/ethnic differences in drug pharmacokinetics in this ethnic group. The racial difference in drug pharmacokinetics seen in American Indian or Alaskan Natives are:

• What class of drug is clonidine?

· Brand of drugs for migraine to treat?

· Nonpharmacologic therapy for tension headaches includes: 1. Biofeedback 2. Stress management 3. Massage therapy 4…… Continue