NR 508 Week 4 Midterm - Study Guide

  • NR 508 Week 4 Midterm - Study Guide
  • $35.00


Institution Chamberlain
Contributor Alfred

Chapter 1: The Role of the Advanced Practice Nurse as Prescriber

Roles and responsibilities of APRN prescribers

Clinical judgement in Prescribing

Questions arises when the choice of treatment option is a drug

  • Is there a clear indication for drug therapy?
  • What drugs are effective in treating this disorder?
  • What is the goal of therapy with this drug?
  • Under what conditions is it determined that a drug is not meeting the goal and a different therapy or drug should be tried?
  • Are there unnecessary duplication with other drugs that the patient is already taking
  • Would an OTC drug be just as useful as a prescription drug?
  • What about the cost?
  • Where is the information to answer this questions?

Collaboration with other providers

Autonomy and Prescriptive authority

 

Chapter 2: Review of Basic Principles of Pharmacology

  • Metabolism: Metabolism & Half Life
  • Drug Responses
  • Receptors: agonists, antagonists
  • Pharmacokinetics: Absorption, Distribution, Protein Binding, Metabolism (including first-pass and Phase I and II)
  • Cytochrome P450 metabolism
  • Excretion: Renal, Biliary, Other (eg for volatile drugs)
  •  

Chapter 3: Rational Drug Selection

Process of rational drug prescribing: 6 Steps proposed by WHO

  • Patient Education
  • Monitor Effectiveness:
  • Drug, Patient, and Provider factors that influence drug selection
  • Influences on Rational Prescribing: Pharmaceutical Promotion
  •  

Chapter 4: Legal and Professional Issues in Prescribing

  • New Drug Approval process including Clinical Phases
  • U.S. FDA Regulatory Jurisdiction:  official labelling vs off-label use of drugs
  •  

Chapter 5: Adverse Drug Reactions

  • Common Causes of ADRs: Risk Factors, including common drugs involved and which cause skin reactions
  • Time-Related Classification of ADRs including drugs associated with withdrawal symptoms
  • Dose-Related ADRs classification
  •  

Chapter 6: Factors that Foster Positive Outcomes

  • Overview of nonadherence:
  • Keys to effective patient education:
  • Health and Cultural beliefs
  • Health Literacy
  • Complexity of Drug Regimen and Polypharmacy
  • Simplifying the Regimen
  •  

Chapter 9: Nutrition and Nutraceuticals

  • Nutrient-Drug Interactions (eg warfarin and vit K)
  • Influence of Diet on Pharmacokinetics of Drugs:
  • Nutraceuticals:

Fiber

Vitamin A

Vitamin B1

Vitamin B2

Vitamin B3

Vitamin B6

Vitamin B12

Vitamin C

Vitamin D

Vitamin K

Folate

Vitamins that are teratogenic in excessive amounts

Vitamins that are useful for migraine prophylaxis

 

 Chapter 12: Pharmacoeconomics

  • Know what Pharmacoeconomics is
  • Impact of Cost: Direct and Indirect
  •  

Chapter 13: Over-the-counter Medications

  • OTC Medication characteristics and regulation
  • OTC Medication Sales
  • Hazards of OTC Self-Medication
  • Adverse Effects of OTC Self-Medication
  • Drug Interactions: antacids, anticholinergics, CNS Depressants, NSAIDS and ASA
  • Abuse of OTC Medications: Combat Methamphetamine Epidemic Act

Chapter 14 Drugs Affecting the Autonomic Nervous System

  • Pharmacodynamics of Alpha2 Agonists
  • Pharmacodynamics of Beta Blockers, adverse effects, what happens with abrupt withdrawal of Beta Blockers?
  • Adverse Drug Reactions
  • Clinical Uses and Dosing of Beta Blockers
  • Muscarinic Agonists:
  •  

Chapter 15 Drugs Affecting the Central Nervous System

  • Anorexiiants:
  • Iminostilbenes:
  • Succinimides:
  • Drugs That Affect GABA:
  • Tricyclic Antidepressants (TCA):
  • Monoamine Oxidase Inhibitors(MAOIs):
  • SSRI:

Chapter 28 Chronic Stable Angina and Low Risk Unstable Angina

  • Additional Patient Variables: Concomitant Diseases
  • Beta Blocker-diabetes Mellitus
  •  

Chapter 36: Heart Failure

  • Indications for heart failure drugs by stage:
  • MOA of ACEIs that benefit heart failure:
  • Indications for use of BBs in patients with heart failure:
  • Drugs that increase life expectancy in patients with heart failure:
  • Digoxin indications and adverse reactions:
  • Drugs contraindicated in heart failure:
  • Drugs for managing heart failure during pregnancy:
  • Patient monitoring of HF:
  • Indications to use anticoagulant therapy:
  • Patient education:
  •  

Chapter 40 Hypertension

  • Classes of drugs used and their MOAs: Nitrates, BBs, CCBs, ACEIs
  • What drugs increase myocardial oxygen supply
  • Causes of hypertension
  • Which drugs treat hypertension & BPH, MI, Heart Failure African Americans.

 

 

Instituition / Term
Term Fall 2019
Institution Chamberlain
Contributor Alfred
 

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