Chapter 1: The Role of the Advanced Practice Nurse as Prescriber
Roles and responsibilities of APRN prescribers
Clinical judgement in Prescribing
Questions arises when the choice of treatment option is a drug
- Is there a clear indication for drug therapy?
- What drugs are effective in treating this disorder?
- What is the goal of therapy with this drug?
- Under what conditions is it determined that a drug is not meeting the goal and a different therapy or drug should be tried?
- Are there unnecessary duplication with other drugs that the patient is already taking
- Would an OTC drug be just as useful as a prescription drug?
- What about the cost?
- Where is the information to answer this questions?
Collaboration with other providers
Autonomy and Prescriptive authority
Chapter 2: Review of Basic Principles of Pharmacology
- Metabolism: Metabolism & Half Life
- Drug Responses
- Receptors: agonists, antagonists
- Pharmacokinetics: Absorption, Distribution, Protein Binding, Metabolism (including first-pass and Phase I and II)
- Cytochrome P450 metabolism
- Excretion: Renal, Biliary, Other (eg for volatile drugs)
Chapter 3: Rational Drug Selection
Process of rational drug prescribing: 6 Steps proposed by WHO
- Patient Education
- Monitor Effectiveness:
- Drug, Patient, and Provider factors that influence drug selection
- Influences on Rational Prescribing: Pharmaceutical Promotion
Chapter 4: Legal and Professional Issues in Prescribing
- New Drug Approval process including Clinical Phases
- U.S. FDA Regulatory Jurisdiction: official labelling vs off-label use of drugs
Chapter 5: Adverse Drug Reactions
- Common Causes of ADRs: Risk Factors, including common drugs involved and which cause skin reactions
- Time-Related Classification of ADRs including drugs associated with withdrawal symptoms
- Dose-Related ADRs classification
Chapter 6: Factors that Foster Positive Outcomes
- Overview of nonadherence:
- Keys to effective patient education:
- Health and Cultural beliefs
- Health Literacy
- Complexity of Drug Regimen and Polypharmacy
- Simplifying the Regimen
Chapter 9: Nutrition and Nutraceuticals
- Nutrient-Drug Interactions (eg warfarin and vit K)
- Influence of Diet on Pharmacokinetics of Drugs:
- Nutraceuticals:
Fiber
Vitamin A
Vitamin B1
Vitamin B2
Vitamin B3
Vitamin B6
Vitamin B12
Vitamin C
Vitamin D
Vitamin K
Folate
Vitamins that are teratogenic in excessive amounts
Vitamins that are useful for migraine prophylaxis
Chapter 12: Pharmacoeconomics
- Know what Pharmacoeconomics is
- Impact of Cost: Direct and Indirect
Chapter 13: Over-the-counter Medications
- OTC Medication characteristics and regulation
- OTC Medication Sales
- Hazards of OTC Self-Medication
- Adverse Effects of OTC Self-Medication
- Drug Interactions: antacids, anticholinergics, CNS Depressants, NSAIDS and ASA
- Abuse of OTC Medications: Combat Methamphetamine Epidemic Act
Chapter 14 Drugs Affecting the Autonomic Nervous System
- Pharmacodynamics of Alpha2 Agonists
- Pharmacodynamics of Beta Blockers, adverse effects, what happens with abrupt withdrawal of Beta Blockers?
- Adverse Drug Reactions
- Clinical Uses and Dosing of Beta Blockers
- Muscarinic Agonists:
Chapter 15 Drugs Affecting the Central Nervous System
- Anorexiiants:
- Iminostilbenes:
- Succinimides:
- Drugs That Affect GABA:
- Tricyclic Antidepressants (TCA):
- Monoamine Oxidase Inhibitors(MAOIs):
- SSRI:
Chapter 28 Chronic Stable Angina and Low Risk Unstable Angina
- Additional Patient Variables: Concomitant Diseases
- Beta Blocker-diabetes Mellitus
Chapter 36: Heart Failure
- Indications for heart failure drugs by stage:
- MOA of ACEIs that benefit heart failure:
- Indications for use of BBs in patients with heart failure:
- Drugs that increase life expectancy in patients with heart failure:
- Digoxin indications and adverse reactions:
- Drugs contraindicated in heart failure:
- Drugs for managing heart failure during pregnancy:
- Patient monitoring of HF:
- Indications to use anticoagulant therapy:
- Patient education:
Chapter 40 Hypertension
- Classes of drugs used and their MOAs: Nitrates, BBs, CCBs, ACEIs
- What drugs increase myocardial oxygen supply
- Causes of hypertension
- Which drugs treat hypertension & BPH, MI, Heart Failure African Americans.
Instituition / Term | |
Term | Fall 2019 |
Institution | Chamberlain |
Contributor | Alfred |