NR 508 Week 1 Outline

  • NR 508 Week 1 Outline
  • $25.00


Institution Chamberlain
Contributor Malissa

Chapter 1: The Role of the Advanced Practice Nurse as Prescriber

  • Roles and responsibilities of APRN prescribers:
  • Clinical judgement in Prescribing:
  • Collaboration with other providers:

Chapter 2: Review of Basic Principles of Pharmacology

  • How Drugs are Developed:
  1. Preclinical stage
  2. Clinical stage
  • Drug Responses:
  • Pharmacokinetics: Absorption, Distribution, Protein Binding, Metabolism (including first-pass and Phase I and II)
  1. Absorption:
  2. Distribution:
  • Protein Binding:
  • Metabolism:
  • Cytochrome P450 metabolism:
  • Excretion:
  • Renal:
  • Biliary:
  • Other:

Chapter 3: Rational Drug Selection

  • Process of rational drug prescribing: 6 Steps proposed by WHO
  1. Define the patient’s problem
  2. Specify therapeutic objective
  3. Choose the treatment
  4. Start the treatment
  5. Educate the patient
  6. Monitor effectiveness
  • Patient education:.
  • Monitor effectiveness:
  • Drug, Patient, and Provider factors that influence drug selection:
  • Influences on Rational Prescribing: Pharmaceutical Promotion:
  • When Prescribing Recommendations Change: antibiotic resistance and overprescribing of antibiotics for URIs:

Chapter 4: Legal and Professional Issues in Prescribing

  • New Drug Approval process including Clinical Phases:
  • U.S. FDA Regulatory Jurisdiction:  
  • Controlled Substance Laws:
  • Controlled Drug DEA schedules (Table 4-1):
  • Controlled Substance Misuse: Prescriber Education
  • Enabling:
  • When you suspect a Patient is Misusing Medications:
  • State Law:
  • Writing and Transmitting the Prescription:
  • Ethical Aspects of Prescribing:

Chapter 5: Adverse Drug Reactions

I.      Mechanistic classification of ADR

II.     Time related ADRS

III.    Dose related ADRS

IV.    Severity of ADRS

V.     Common causes of ADRS

VI.    Risk factors

Chapter 6: Factors that Foster Positive Outcomes

  • Overview of nonadherence
  • Keys to effective patient education
  • Health and Cultural beliefs
  • Health Literacy
  • Complexity of Drug Regimen and Polypharmacy
  • Collaborative management
  • 4 steps
  • Personalized drug schedules
  • Simplifying the Regimen
  • Communication Difficulties

Chapter 7: Cultural and Ethnic Influences in Pharmacotherapeutics

  • Cultural Influences on Care
  • Ethnopharmacology

Chapter 9: Nutrition and Nutraceuticals

  • Nutrient-Drug Interactions (eg warfarin and vit K)
  • Outcomes of Nutrient-Drug Interactions

Chapter 12: Pharmacoeconomics

  • Impact of Generic Drugs on Drug Therapy
  • Generic Substitution
  • Prescribing Generic vs Brand-Name Medications:  

Chapter 13: Over-the-counter Medications

Chapter 24: Drugs Used in Treating Infectious Diseases

  • Antimicrobial Resistance:
  • Antibiotics:
  • Beta-Lactams:
  • Acute Bronchitis and URI, Sinusitis
  1. Sinusitis:
  1. Acute Bronchitis and URI
  2. Pharyngitis:
  3. UTIS
  4. Skin and Tissue Infections(p. 700)
  5. H. pylori eradications (p. 700)
  6. Age, Pregnancy and Genetic Factors(p. 705)
  7. Fluoroquinolones:
  8. Macrolides:
  9. Systemic Azoles and other Antifungals:
  10. Sulfonamides, Trimethoprim, Nitrofurantoin and Fosfomycin:
  11. Tetracyclines:
  12. Antimycobacterials:
  13. Nucleoside Analogues:
  14. Antivirals for Influenza:

 

 

Instituition / Term
Term Session 2019
Institution Chamberlain
Contributor Malissa
 

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