NR 507 Week 4 Notes-Alterations in renal and urinary function

  • NR 507 Week 4 Notes-Alterations in renal and urinary function
  • $10.00


Institution NR 507 Advanced Pathophysiology
Contributor Mireille

Alterations in renal and urinary function

  • Structures of the renal system
    • kidneys
      • paired organs located in the posterior region of the abdominal cavity behind the peritoneum
      • right kidney slightly lower than the left and displace towered by the overlying liver
      • the renal capsule surrounds each kidney and the kidney is embedded in a mass of fat
      • the capsule and fatty layer are covered with a double layer of renal fascia compose the fibrous tissues that attach the kidney to the posterior abdominal wall
        • the cushion of fat and the position of the kidney between the abdominal organs and muscles of the back protected from trauma
      • hilum-medial indentation in the kidney and is the location of entry and exit for the renal blood vessels, nerves, lymphatic vessels, and ureter.
      • Structures of kidney:
        • Cortex-outer layer; contains glomeruli, most proximal tubules, and some segments of the distal tubule
          • renal columns-extension of the cortex; lie between the pyramids an extend to the renal pelvis
        • Medulla-inner part of the kidney; consists of the pyramids
          • minor calyces (Cup shaped cavities)-apexes of the pyramids project into these
          • major calyces-minor calyces unite to form these
            • Join to form the renal pelvis
        • renal pelvis-connects with the proximal end of the ureter
        • lobe-the structural unit of the kidney
          • each lobe is composed of a pyramid and overlying cortex
            • about 14 lobes in each kidney
        • nephron-functional unit of the kidney
          • each kidney contains about 1.2 million nephrons
  •  

    • the renal corpuscle
      • bowman capsule
        • glomerulus
      • proximal convoluted tubule

    • loop of Henle (nephron ansa)
    • distal convoluted tubule
    • collecting duct
  • all of these contribute to the formation of urine
    • the different epithelial cells lining various segments of the tubule facilitate the special functions of reabsorption and secretion
    • three kinds of nephrons:
      • superficial cortical nephrons (85%)-extend partially into the medulla
      • midcortical nephrons with short or long loops
      • juxtamedullary nephrons-like close to an extend deep into the medulla; important for the concentration of urine
  •  

 

Instituition / Term
Term Year 2022
Institution NR 507 Advanced Pathophysiology
Contributor Mireille
 

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